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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Scientists have found that the protein histone H1.2 and the enzyme PARP1 could be potential therapeutic targets to decrease neurodegeneration in amyotrophic lateral sclerosis (ALS). Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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A new brain-computer interface translates brain signals into speech with up to 97 percent accuracy. Researchers implanted sensors in the brain of a man with severely impaired speech due to amyotrophic lateral sclerosis (ALS). The man was able to communicate his intended speech within minutes of...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Researchers have used a new technique to identify pathological abnormalities associated with motor neurone disease. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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The study provides the basis for a phase I clinical trial in additional participants. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Defects in the blood vessel network of the central nervous system have been linked to early symptoms of neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS). It is this complex vascular network that provides the necessary nutrients -- especially glucose...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Participation in recreational activities -- including golfing, gardening or yard work, woodworking and hunting -- may be associated with an increase in a person's risk for developing ALS. Researchers found that golf was associated with three times greater risk for developing ALS among men...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Scientists have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their research pinpointed a misbehaving protein as a promising therapeutic target in the treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS). Neurobiologists examined a neuroprotective molecule that...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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In people with amyotrophic lateral sclerosis (ALS), changes in neurons appear to activate immune cells. Lowering the inflammation could reduce the symptoms of the disease, according to a new study. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Scientists identify ALS-linked protein VAP as a key stabilizer of mitochondria near dendritic spines to support memory formation. This finding opens new directions for research into cognitive and motor learning impairments in ALS. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and neurodegeneration is clear, it is still unclear in what way misfolded proteins trigger cell death. A team...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control. Scientists have now suggested a potential therapeutic strategy to tackle this pathology that has no treatment to date. It is a molecular trap that...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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A research group has found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan of and alleviates disease symptoms in rats and mice in animal studies. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Researchers have developed an evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Amyotrophic lateral sclerosis (ALS) is a widespread neurodegenerative disease caused by the loss of neurons that control movement. Although abnormal accumulation of proteins called TDP-43 accompanies ALS, its role in disease progression is not well understood. Recently, using novel mouse models...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Researchers have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS). Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms and providing supportive care. Researchers now show in an...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS. Lue lisää...
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Amyotrophic Lateral Sclerosis News -- ScienceDaily
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Researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma. Lue lisää...
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